RRM1 antibody (AA 129-730)

Catalog No. ABIN7870448

This Rabbit Polyclonal antibody specifically detects RRM1 in WB, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for RRM1 antibody (AA 129-730) (ABIN7870448)

Target: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RRM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-RRM1 Antibody

Binding Specificity: AA 129-730

Purpose: Ribonucleotide Reductase M1 Antibody / RRM1

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids D129-Q730) was used as the immunogen for the Ribonucleotide Reductase M1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Ribonucleotide Reductase M1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Ribonucleotide Reductase M1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for RRM1

Target: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Alternative Name: Ribonucleotide Reductase M1

Background: Ribonucleoside-diphosphate reductase large subunit is an enzyme that in humans is encoded by the RRM1 gene. This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multiple transcript variants.

UniProt: P23921

Pathways: Positive Regulation of Endopeptidase Activity