ESRRA antibody (AA 131-159)

Catalog No. ABIN7870502

This Rabbit Polyclonal antibody specifically detects ESRRA in WB, FACS, IF and IHC (p). It exhibits reactivity toward Human.

Quick Overview for ESRRA antibody (AA 131-159) (ABIN7870502)

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ESRRA antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ESRRA Antibody

Binding Specificity: AA 131-159

Purpose: Estrogen-Related Receptor Alpha Antibody / ESRRA

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 131-159 from the human protein was used as the immunogen for the Estrogen-Related Receptor Alpha antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Estrogen-Related Receptor Alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Estrogen-Related Receptor Alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for ESRRA

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Alternative Name: Estrogen-Related Receptor Alpha

Background: ESRRA is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes.

UniProt: P11474

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha