HRPT2 antibody (AA 132-161)

Catalog No. ABIN7870512

The Rabbit Polyclonal anti-HRPT2 antibody is suitable to detect HRPT2 in samples from Human. It has been validated for WB, IF, FACS and IHC (p).

Quick Overview for HRPT2 antibody (AA 132-161) (ABIN7870512)

Target: HRPT2 (CDC73) (Parafibromin (CDC73))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HRPT2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-HRPT2 Antibody

Binding Specificity: AA 132-161

Purpose: CDC73 Antibody

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 132-161 from the human protein were used as the immunogen for the CDC73 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the CDC73 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CDC73 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for HRPT2

Target: HRPT2 (CDC73) (Parafibromin (CDC73))

Alternative Name: CDC73

Background: CDC73 encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin.

UniProt: Q6P1J9

Pathways: Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance