MMP15 antibody (AA 132-202)

Catalog No. ABIN7870513

The Rabbit Polyclonal anti-MMP15 antibody (ABIN7870513) specifically detects MMP15 in WB, ELISA, FACS and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for MMP15 antibody (AA 132-202) (ABIN7870513)

Target: MMP15 (Matrix Metallopeptidase 15 (Membrane-inserted) (MMP15))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP15 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Product Details anti-MMP15 Antibody

Binding Specificity: AA 132-202

Purpose: MT2-MMP Antibody / MMP15

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids Y132-A202) was used as the immunogen for the MT2-MMP antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the MT2-MMP antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the MT2-MMP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for MMP15

Target: MMP15 (Matrix Metallopeptidase 15 (Membrane-inserted) (MMP15))

Alternative Name: MT2-MMP

Background: Matrix metalloproteinase 15 (MMP15) also known as Membrane-type-2 matrix metalloproteinase (MT2-MMP) is an enzyme that in humans is encoded by the MMP15 gene. This gene encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein may play a role in cancer progression.

UniProt: P51511