LIN28A antibody (AA 134-187)

Catalog No. ABIN7870532

This Mouse Monoclonal antibody specifically detects LIN28A in FACS. It exhibits reactivity toward Human.

Quick Overview for LIN28A antibody (AA 134-187) (ABIN7870532)

Target: LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LIN28A antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: PCRP-LIN28A-1E2

Product Details anti-LIN28A Antibody

Binding Specificity: AA 134-187

Purpose: LIN28A Antibody

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 134-187) from the human protein was used as the immunogen for the LIN28A antibody.

Isotype: IgG2a

Application Details

Application Notes: Optimal dilution of the LIN28A antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the LIN28A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for LIN28A

Target: LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

Alternative Name: LIN28A

Background: LIN-28 is a highly conserved, RNA-binding, cytoplasmic protein. It consists of a cold shock domain and retroviral-type (CCHC) zinc finger motifs that were first identified in Caenorhabditis elegans. LIN-28 controls the timing of events during embryonic development and is readily expressed in embryos, embryonic stem cells and embryonal carcinoma cells. The presence of LIN-28 persists in some adult tissues including cardiac and skeletal muscle. In differentiating myoblasts, LIN-28 increases protein synthesis efficiency and binds to the growth and differentiation factor IGF-II.

UniProt: Q9H9Z2

Pathways: Stem Cell Maintenance