14-3-3 gamma antibody (AA 136-164)

Catalog No. ABIN7870551

The Rabbit Polyclonal anti-14-3-3 gamma antibody is suitable to detect 14-3-3 gamma in samples from Human and Mouse. It has been validated for WB, FACS and IHC (p).

Quick Overview for 14-3-3 gamma antibody (AA 136-164) (ABIN7870551)

Target: 14-3-3 gamma (YWHAG1)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This 14-3-3 gamma antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-14-3-3 gamma Antibody

Binding Specificity: AA 136-164

Purpose: YWHAG Antibody / 14-3-3 gamma

Purification: SAS precipitation

Immunogen: A portion of amino acids 136-164 from the human protein was used as the immunogen for the YWHAG antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the YWHAG antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the YWHAG antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for 14-3-3 gamma

Target: 14-3-3 gamma (YWHAG1)

Alternative Name: YWHAG

Background: YWHAG belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100 % identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.

UniProt: P61981

Pathways: Myometrial Relaxation and Contraction, M Phase