Complement Factor H antibody (AA 136-447)

Catalog No. ABIN7870556

This Rabbit Polyclonal antibody specifically detects Complement Factor H in WB, FACS and IHC (p). It exhibits reactivity toward Rat and Mouse.

Quick Overview for Complement Factor H antibody (AA 136-447) (ABIN7870556)

Target: Complement Factor H (CFH)

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Complement Factor H antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Complement Factor H Antibody

Binding Specificity: AA 136-447

Purpose: Cfh Antibody / Factor H

Purification: Affinity purified

Immunogen: Recombinant mouse protein (amino acids N136-T447) was used as the immunogen for the Cfh antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Cfh antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Cfh antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Complement Factor H

Target: Complement Factor H (CFH)

Alternative Name: Cfh

Background: Factor H is a member of the regulators of complement activation family and is a complement control protein. This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

UniProt: P06909

Pathways: Complement System, Cellular Response to Molecule of Bacterial Origin