ETS1 antibody (AA 137-230)

Catalog No. ABIN7870571

This Mouse Monoclonal antibody specifically detects ETS1 in ELISA. It exhibits reactivity toward Human.

Quick Overview for ETS1 antibody (AA 137-230) (ABIN7870571)

Target: ETS1 (V-Ets erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) (ETS1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ETS1 antibody is un-conjugated

Application: ELISA

Clone: ETS1-1801

Product Details anti-ETS1 Antibody

Binding Specificity: AA 137-230

Purpose: ETS1 Antibody

Purification: Protein G affinity chromatography

Immunogen: A recombinant human partial protein (amino acids 137-230) was used as the immunogen for the ETS1 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the ETS1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the ETS1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for ETS1

Target: ETS1 (V-Ets erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) (ETS1))

Alternative Name: ETS1

Background: ETS1 proto-oncogene is an important transcription factor that plays a role in cell proliferation and differentiation. ETS1 is related to the growth of carcinoma cells by its regulation of the transcription of matrix metalloproteinases and urokinase-type plasminogen activator.The processes of tumor invasion and metastasis depend on the increased proteolytic activity of the invading tumor cells that may involve matrix metalloproteinases, cathepsins B and D and plasminogen activator in the metastatic cascade. ETS1 is preferentially expressed in lymphoid cells, where it is essential for the maintenance of the normal pool of resting T and B cells.ETS1 expression level and distribution are differentially controlled in resting, activated and apoptotic lymphocytes.

UniProt: P14921