CTNND1 antibody (AA 138-276)

Catalog No. ABIN7870586

This Mouse Monoclonal antibody specifically detects CTNND1 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for CTNND1 antibody (AA 138-276) (ABIN7870586)

Target: CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CTNND1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CTNND1-4501

Product Details anti-CTNND1 Antibody

Binding Specificity: AA 138-276

Purpose: Delta 1 Catenin Antibody / CTNND1 / p120 Catenin

Purification: Protein A/G affinity

Immunogen: A portion of amino acids 138-276 was used as the immunogen for the Delta 1 Catenin antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the Delta 1 Catenin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Delta 1 Catenin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CTNND1

Target: CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

Alternative Name: Delta 1 Catenin

Background: Alpha-catenin and beta-catenin bind to the intracellular domain of E-cadherin while p120 catenin (delta-1-catenin) binds E-cadherin at a juxta-membrane site. The complex stabilizes tight junctions. In the cell, delta-1-catenin localized to the E-cadherin/catenins cell adhesion complex, directly associates with cytoplasmic C-terminus of E-cadherin and may similarly interact with other cadherins.

UniProt: O60716

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling