NSMCE2 antibody (AA 14-228)

Catalog No. ABIN7870621

The Rabbit Polyclonal anti-NSMCE2 antibody (ABIN7870621) specifically detects NSMCE2 in WB, ELISA, FACS, IF and IP. The antibody is reactive with Human samples.

Quick Overview for NSMCE2 antibody (AA 14-228) (ABIN7870621)

Target: NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NSMCE2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-NSMCE2 Antibody

Binding Specificity: AA 14-228

Purpose: NSMCE2 Antibody / NSE2 / MMS21

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (F14-D228) was used as the immunogen for the NSMCE2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the NSMCE2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the NSMCE2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for NSMCE2

Target: NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))

Alternative Name: NSMCE2

Background: This gene encodes a member of a family of E3 small ubiquitin-related modifier (SUMO) ligases that mediates the attachment of a SUMO protein to proteins involved in nuclear transport, transcription, chromosome segregation and DNA repair. The encoded protein is part of the structural maintenance of chromosomes (SMC) 5/6 complex which plays a key role genome maintenance, facilitating chromosome segregation and suppressing mitotic recombination. A knockout of the orthologous mouse gene is lethal prior to embryonic day 10.5. Naturally occurring mutations in this gene, that abolish the SUMO ligase activity, are associated with primordial dwarfism and extreme insulin resistance.

UniProt: Q96MF7