ADRM1 antibody (AA 14-385)

Catalog No. ABIN7870629

The Rabbit Polyclonal anti-ADRM1 antibody is suitable to detect ADRM1 in samples from Zebrafish (Danio rerio). It has been validated for WB and IHC (p).

Quick Overview for ADRM1 antibody (AA 14-385) (ABIN7870629)

Target: ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADRM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ADRM1 Antibody

Binding Specificity: AA 14-385

Purpose: Zebrafish Adrm1 Antibody / Adrm1b

Purification: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish Adrm1 recombinant protein (amino acids S14-M385) was used as the immunogen for the Zebrafish Adrm1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal dilution of the Zebrafish Adrm1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Zebrafish Adrm1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ADRM1

Target: ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

Alternative Name: Adrm1

Background: Proteasomal ubiquitin receptor ADRM1 is a protein that in humans is encoded by the ADRM1 gene. This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants.

UniProt: Q6NZ09

Pathways: Positive Regulation of Endopeptidase Activity