RCC1 antibody (AA 14-421)

Catalog No. ABIN7870638

The Mouse Monoclonal anti-RCC1 antibody is suitable to detect RCC1 in samples from Human. It has been validated for WB.

Quick Overview for RCC1 antibody (AA 14-421) (ABIN7870638)

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RCC1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 7B5D2

Product Details anti-RCC1 Antibody

Binding Specificity: AA 14-421

Purpose: Regulator of Chromosome Condensation Antibody / RCC1 / CHC1

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids A14-S421) was used as the immunogen for the Regulator of Chromosome Condensation antibody.

Isotype: IgG1

Application Details

Application Notes: Optimal dilution of the Regulator of Chromosome Condensation antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Regulator of Chromosome Condensation antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for RCC1

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Alternative Name: Regulator of Chromosome Condensation

Background: Regulator of Chromosome Condensation, also named RCC1, SNHG3-RCC1 and CHC1 (Chromosome condensation protein 1), promotes the exchange of ran-bound gdp by gtp. It is involved in the regulation of onset of chromosome condensation in the S-phase. Phosphorylation of RCC1 on serines located in or near its nuclear localization signal activates RCC1 to generate RanGTP on mitotic chromosomes, which is required for spindle assembly and chromosome segregation.

UniProt: P18754

Pathways: Chromatin Binding, Protein targeting to Nucleus