RCC1 antibody (AA 14-421)

Catalog No. ABIN7870639

The Rabbit Polyclonal anti-RCC1 antibody (ABIN7870639) specifically detects RCC1 in WB, ELISA, IF, FACS and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for RCC1 antibody (AA 14-421) (ABIN7870639)

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RCC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RCC1 Antibody

Binding Specificity: AA 14-421

Purpose: RCC1 Antibody / Regulator of Chromosome Condensation

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids A14-S421) was used as the immunogen for the RCC1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the RCC1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the RCC1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for RCC1

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Alternative Name: RCC1

Background: CHC1, also named as RCC1, SNHG3-RCC1, promotes the exchange of ran-bound gdp by gtp. It is involved in the regulation of onset of chromosome condensation in the S-phase. Phosphorylation of RCC1 on serines located in or near its nuclear localization signal activates RCC1 to generate RanGTP on mitotic chromosomes, which is required for spindle assembly and chromosome segregation. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human RCC1. The geneID has updated as 1104 recently.

UniProt: P18754

Pathways: Chromatin Binding, Protein targeting to Nucleus