NCOA4 antibody (AA 14-614)

Catalog No. ABIN7870652

This Rabbit Polyclonal antibody specifically detects NCOA4 in WB, ELISA and FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for NCOA4 antibody (AA 14-614) (ABIN7870652)

Target: NCOA4 (Nuclear Receptor Coactivator 4 (NCOA4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCOA4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-NCOA4 Antibody

Binding Specificity: AA 14-614

Purpose: NCOA4 Antibody / Nuclear receptor coactivator 4

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids R14-M614) was used as the immunogen for the NCOA4 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the NCOA4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the NCOA4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for NCOA4

Target: NCOA4 (Nuclear Receptor Coactivator 4 (NCOA4))

Alternative Name: NCOA4

Background: Nuclear receptor coactivator 4 is a protein that in humans is encoded by the NCOA4 gene. This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14.

UniProt: Q13772

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway