The Rabbit Polyclonal anti-SLBP antibody is suitable to detect SLBP in samples from Human and Mouse. It has been validated for WB, ELISA, IF, FACS and IHC (p).
SLBP
Reactivity: Human, Cow
WB, IP
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Optimal dilution of the SLBP antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Storage
4 °C,-20 °C
Storage Comment
After reconstitution, the SLBP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Target
SLBP
(Stem-Loop Binding Protein (SLBP))
Alternative Name
SLBP
Background
Histone RNA hairpin-binding protein is a protein that in human is encoded by the SLBP gene. This gene is mapped to 4p16.3. This gene encodes a protein that binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1.