WFDC1 antibody (AA 148-177)

Catalog No. ABIN7870752

The Rabbit Polyclonal anti-WFDC1 antibody is suitable to detect WFDC1 in samples from Human. It has been validated for WB, FACS and IHC (p).

Quick Overview for WFDC1 antibody (AA 148-177) (ABIN7870752)

Target: WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WFDC1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-WFDC1 Antibody

Binding Specificity: AA 148-177

Purpose: WFDC1 Antibody

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 148-177 from the human protein was used as the immunogen for the WFDC1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the WFDC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the WFDC1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for WFDC1

Target: WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))

Alternative Name: WFDC1

Background: This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. The encoded protein shares 81 % amino acid identity with the rat ps20 protein, which was originally identified as a secreted growth inhibitor. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. Owing to its location and a possible growth inhibitory property of its gene product, this gene is suggested to be a tumor suppressor gene.

UniProt: Q9HC57