POU2AF1 antibody (AA 148-255)

Catalog No. ABIN7870757

This Mouse Monoclonal antibody specifically detects POU2AF1 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for POU2AF1 antibody (AA 148-255) (ABIN7870757)

Target: POU2AF1 (POU Class 2 Associating Factor 1 (POU2AF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This POU2AF1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: BOB1-7469

Product Details anti-POU2AF1 Antibody

Binding Specificity: AA 148-255

Purpose: BOB-1 Antibody / POU2AF1 (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein (within amino acids 148-255) from the human protein was used as the immunogen for the BOB-1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the BOB-1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the BOB-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for POU2AF1

Target: POU2AF1 (POU Class 2 Associating Factor 1 (POU2AF1))

Alternative Name: BOB-1

Background: BOB.1 expression in a variety of established B-cell lines, representing different stages of B-cell development, has suggested a constitutive, B-cell-specific expression pattern. LP cells in nodular lymphocyte predominant Hodgkin lymphoma, because they are germinal center-derived, are consistently immuno-positive for BOB.1. Conversely, only some cases of classical Hodgkin lymphoma show BOB.1 immuno-reactivity within the Hodgkin and Reed-Sternberg cells. Expression of BOB.1 has been reported in follicular center cell lymphoma, diffuse large B-cell lymphoma and some cases of acute myeloid leukemia. B-CLL, marginal zone lymphoma, and mantle cell lymphoma may show weak to moderate immunoreactivity.

UniProt: Q16633