POU2AF1 antibody (AA 148-255)

Catalog No. ABIN7870764

The Mouse Monoclonal anti-POU2AF1 antibody is suitable to detect POU2AF1 in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for POU2AF1 antibody (AA 148-255) (ABIN7870764)

Target: POU2AF1 (POU Class 2 Associating Factor 1 (POU2AF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This POU2AF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: PD2AF1-1

Product Details anti-POU2AF1 Antibody

Binding Specificity: AA 148-255

Purpose: BOB1 Antibody

Purification: Protein G affinity

Immunogen: A portion of amino acids 148-255 from the human protein was used as the immunogen for the BOB1 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the BOB1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the BOB1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for POU2AF1

Target: POU2AF1 (POU Class 2 Associating Factor 1 (POU2AF1))

Alternative Name: BOB1

Background: Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers. [UniProt]

UniProt: Q16633