PNPLA6 antibody (AA 15-1296)

Catalog No. ABIN7870780

The Rabbit Polyclonal anti-PNPLA6 antibody (ABIN7870780) specifically detects PNPLA6 in WB, ELISA, IF and FACS. The antibody is reactive with Human samples.

Quick Overview for PNPLA6 antibody (AA 15-1296) (ABIN7870780)

Target: PNPLA6 (Patatin-Like phospholipase Domain Containing 6 (PNPLA6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PNPLA6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-PNPLA6 Antibody

Binding Specificity: AA 15-1296

Purpose: PNPLA6 Antibody / NTE

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids H15-E1296) was used as the immunogen for the PNPLA6 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PNPLA6 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PNPLA6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PNPLA6

Target: PNPLA6 (Patatin-Like phospholipase Domain Containing 6 (PNPLA6))

Alternative Name: PNPLA6

Background: Neuropathy target esterase (NTE), also known as patatin-like phospholipase domain-containing protein 6 (PNPLA6), is an esterase enzyme that in humans is encoded by the PNPLA6 gene. This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: Q8IY17

Pathways: Ribonucleoside Biosynthetic Process