ABI2 antibody (AA 151-400)

Catalog No. ABIN7870974

The Rabbit Polyclonal anti-ABI2 antibody is suitable to detect ABI2 in samples from Human and Rat. It has been validated for WB, ELISA, IF, FACS and IHC (p).

Quick Overview for ABI2 antibody (AA 151-400) (ABIN7870974)

Target: ABI2 (Abl-Interactor 2 (ABI2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABI2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ABI2 Antibody

Binding Specificity: AA 151-400

Purpose: Abelson interactor 2 Antibody / ABI2

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids H151-D400) was used as the immunogen for the Abelson interactor 2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Abelson interactor 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Abelson interactor 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ABI2

Target: ABI2 (Abl-Interactor 2 (ABI2))

Alternative Name: Abelson interactor 2

Background: Abl interactor 2 also known as Abelson interactor 2 (Abi-2) is a protein that in humans is encoded by the ABI2 gene. Enables several functions, including SH3 domain binding activity, identical protein binding activity, and ubiquitin protein ligase binding activity. Contributes to small GTPase binding activity. Involved in Rac protein signal transduction, positive regulation of cellular component organization, and zonula adherens assembly. Acts upstream of or within peptidyl-tyrosine phosphorylation. Located in several cellular components, including filopodium tip, lamellipodium, and nucleoplasm. Part of SCAR complex. Is active in adherens junction. Colocalizes with actin filament.

UniProt: Q9NYB9