FTH1 antibody (Heavy Chain)

Catalog No. ABIN7870996

The Rabbit Polyclonal anti-FTH1 antibody (ABIN7870996) specifically detects FTH1 in WB, FACS and IHC (p). The antibody is reactive with Human samples.

Quick Overview for FTH1 antibody (Heavy Chain) (ABIN7870996)

Target: FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FTH1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FTH1 Antibody

Binding Specificity: AA 154-183, Heavy Chain

Purpose: Ferritin heavy chain Antibody / FTH1

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 154-183 from the human protein was used as the immunogen for the Ferritin heavy chain antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Ferritin heavy chain antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Ferritin heavy chain antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for FTH1

Target: FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

Alternative Name: Ferritin heavy chain

Background: FTH1 is the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases.

UniProt: P02794

Pathways: Transition Metal Ion Homeostasis