GCAT antibody (AA 155-181)

Catalog No. ABIN7871005

The Rabbit Polyclonal anti-GCAT antibody (ABIN7871005) specifically detects GCAT in WB, FACS and IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for GCAT antibody (AA 155-181) (ABIN7871005)

Target: GCAT (Glycine C-Acetyltransferase (GCAT))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCAT antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GCAT Antibody

Binding Specificity: AA 155-181

Purpose: GCAT Antibody / Glycine acetyltransferase

Purification: Purified

Immunogen: A portion of amino acids 155-181 from the human protein was used as the immunogen for the GCAT antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the GCAT antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the GCAT antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for GCAT

Target: GCAT (Glycine C-Acetyltransferase (GCAT))

Alternative Name: GCAT

Background: The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. GCAT is the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase.

UniProt: O75600