SRSF1 antibody (AA 158-186)

Catalog No. ABIN7871026

The Rabbit Polyclonal anti-SRSF1 antibody (ABIN7871026) specifically detects SRSF1 in WB, FACS and IHC (p). The antibody is reactive with Human samples.

Quick Overview for SRSF1 antibody (AA 158-186) (ABIN7871026)

Target: SRSF1 (serine/arginine-Rich Splicing Factor 1 (SRSF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRSF1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SRSF1 Antibody

Binding Specificity: AA 158-186

Purpose: SRSF1 Antibody / SF2

Purification: Purified

Immunogen: A portion of amino acids 158-186 from the human protein was used as the immunogen for the SRSF1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the SRSF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the SRSF1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for SRSF1

Target: SRSF1 (serine/arginine-Rich Splicing Factor 1 (SRSF1))

Alternative Name: SRSF1

Background: SRSF1 is a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. The protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The protein's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins.

UniProt: Q07955

Pathways: Ribonucleoprotein Complex Subunit Organization