TRIP4 antibody (AA 158-563)

Catalog No. ABIN7871028

The Rabbit Polyclonal anti-TRIP4 antibody is suitable to detect TRIP4 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for TRIP4 antibody (AA 158-563) (ABIN7871028)

Target: TRIP4 (Thyroid Hormone Receptor Interactor 4 (TRIP4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIP4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TRIP4 Antibody

Binding Specificity: AA 158-563

Purpose: ASC1 Antibody / TRIP-4

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids Q158-D563) was used as the immunogen for the ASC1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ASC1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ASC1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for TRIP4

Target: TRIP4 (Thyroid Hormone Receptor Interactor 4 (TRIP4))

Alternative Name: ASC1

Background: Activating signal cointegrator 1 is a protein that in humans is encoded by the TRIP4 gene. This gene encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 (ASC-1) complex, which associates with transcriptional coactivators, nuclear receptors and basal transcription factors to facilitate nuclear receptors-mediated transcription. This protein is localized in the nucleus and contains an E1A-type zinc finger domain, which mediates interaction with transcriptional coactivators and ligand-bound nuclear receptors, such as thyroid hormone receptor and retinoid X receptor alpha, but not glucocorticoid receptor. Mutations in this gene are associated with spinal muscular atrophy with congenital bone fractures-1 (SMABF1).

UniProt: Q15650