AFG3L2 antibody (AA 161-245)

Catalog No. ABIN7871108

This Rabbit Polyclonal antibody specifically detects AFG3L2 in WB. It exhibits reactivity toward Zebrafish (Danio rerio).

Quick Overview for AFG3L2 antibody (AA 161-245) (ABIN7871108)

Target: AFG3L2 (AFG3-Like Protein 2 (AFG3L2))

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AFG3L2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AFG3L2 Antibody

Binding Specificity: AA 161-245

Purpose: Zebrafish Afg3l2 Antibody / AFG3 like protein 2

Purification: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish Afg3l2 recombinant protein (amino acids G161-D245) was used as the immunogen for the Zebrafish Afg3l2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal dilution of the Zebrafish Afg3l2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Zebrafish Afg3l2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for AFG3L2

Target: AFG3L2 (AFG3-Like Protein 2 (AFG3L2))

Alternative Name: Afg3l2

Background: AFG3L2 is the catalytic subunit of the m-AAA protease, an ATP-dependent proteolytic complex of the mitochondrial inner membrane that degrades misfolded proteins and regulates ribosome assembly. In humans, it is encoded by the AFG3L2 gene. This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. And this gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders as well as spastic ataxia-neuropathy syndrome.

UniProt: A9JRG9

Pathways: Skeletal Muscle Fiber Development