Cathepsin K antibody (AA 163-274)

Catalog No. ABIN7871120

This Mouse Monoclonal antibody specifically detects Cathepsin K in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Cathepsin K antibody (AA 163-274) (ABIN7871120)

Target: Cathepsin K (CTSK)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cathepsin K antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CTO2-1

Product Details anti-Cathepsin K Antibody

Binding Specificity: AA 163-274

Purpose: CTSK Antibody / Cathepsin K

Purification: Protein G affinity chromatography

Immunogen: Amino acids 163-274 were used as the immunogen for the CTSK antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the CTSK antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the CTSK antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Cathepsin K

Target: Cathepsin K (CTSK)

Alternative Name: CTSK

Background: Closely involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH . May play an important role in extracellular matrix degradation. [UniProt]

UniProt: P43235

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades