SRF antibody (AA 163-508)

Catalog No. ABIN7871127

The Rabbit Polyclonal anti-SRF antibody is suitable to detect SRF in samples from Human. It has been validated for WB, ELISA, IF, IHC (p) and FACS.

Quick Overview for SRF antibody (AA 163-508) (ABIN7871127)

Target: SRF (Serum Response Factor (SRF))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRF antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-SRF Antibody

Binding Specificity: AA 163-508

Purpose: SRF Antibody / Serum Response Factor

Purification: Affinity purified

Immunogen: An E. coli-derived human protein (amino acids K163-E508) was used as the immunogen for the SRF antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SRF antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the SRF antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SRF

Target: SRF (Serum Response Factor (SRF))

Alternative Name: SRF

Background: Serum response factor, also known as SRF, is a transcription factor protein. This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways, for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene.

UniProt: P11831