PCDHa13 antibody (AA 165-349)

Catalog No. ABIN7871145

The Rabbit Polyclonal anti-PCDHa13 antibody is suitable to detect PCDHa13 in samples from Human. It has been validated for WB, ELISA and FACS.

Quick Overview for PCDHa13 antibody (AA 165-349) (ABIN7871145)

Target: PCDHa13 (Protocadherin alpha 13 (PCDHa13))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHa13 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-PCDHa13 Antibody

Binding Specificity: AA 165-349

Purpose: PCDHA13 Antibody / Protocadherin alpha-13

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (amino acids N165-E349) was used as the immunogen for the PCDHA13 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PCDHA13 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PCDHA13 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PCDHa13

Target: PCDHa13 (Protocadherin alpha 13 (PCDHa13))

Alternative Name: PCDHA13

Background: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

UniProt: Q9Y5I0