TLN1 antibody (AA 1658-1876)

Catalog No. ABIN7871152

The Rabbit Polyclonal anti-TLN1 antibody (ABIN7871152) specifically detects TLN1 in WB, ELISA, IF, IHC (p) and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TLN1 antibody (AA 1658-1876) (ABIN7871152)

Target: TLN1 (Talin 1 (TLN1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-TLN1 Antibody

Binding Specificity: AA 1658-1876

Purpose: TLN1 Antibody / Talin 1

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids Q1658-N1876) was used as the immunogen for the TLN1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the TLN1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the TLN1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for TLN1

Target: TLN1 (Talin 1 (TLN1))

Alternative Name: TLN1

Background: Talin-1 is a protein that in humans is encoded by the TLN1 gene. This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.

UniProt: Q9Y490

Pathways: Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location