Flotillin 2 antibody (AA 169-344)

Catalog No. ABIN7871202

The Mouse Monoclonal anti-Flotillin 2 antibody is suitable to detect Flotillin 2 in samples from Human, Rat and Mouse. It has been validated for WB, IHC (p) and IF.

Quick Overview for Flotillin 2 antibody (AA 169-344) (ABIN7871202)

Target: Flotillin 2 (FLOT2)

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Flotillin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Clone: 4D8A3

Product Details anti-Flotillin 2 Antibody

Binding Specificity: AA 169-344

Purpose: FLOT2 Antibody / Flotillin 2

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids K169-K344) was used as the immunogen for the FLOT2 antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the FLOT2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the FLOT2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Flotillin 2

Target: Flotillin 2 (FLOT2)

Alternative Name: FLOT2

Background: FLOT2 (Flotillin 2), also known as ESA1 or M17S1, is a protein that in humans is encoded by the FLOT2 gene. Schroeder et al. (1991) isolated a cDNA for an epidermal surface antigen believed to be involved in epidermal cell adhesion. By analysis of a somatic cell hybrid panel and in situ hybridization using the ESA cDNA, the gene was mapped to 17q11-q12 in the region containing the NF1 gene. Bickel et al. (1997) found that mouse Flot2 consistently copurifies with Flot1 and with caveolin-1 in the purification of caveolin-rich membranes. Using a quantitative proteomic analysis of cultured mouse neuronal stem cells, Li et al. (2012) found that palmitoylation and oligomerization of flotillin-2 was abolished in homozygous Dhhc5 mutant neuronal stem cells. The absolute amount of flotillin-2 was not changed in Dhhc5 mutant neurons.

UniProt: Q14254