HPRT1 antibody (AA 17-185)

Catalog No. ABIN7871210

This Rabbit Polyclonal antibody specifically detects HPRT1 in WB and IHC (p). It exhibits reactivity toward Zebrafish (Danio rerio).

Quick Overview for HPRT1 antibody (AA 17-185) (ABIN7871210)

Target: HPRT1 (Hypoxanthine phosphoribosyltransferase 1 (HPRT1))

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HPRT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-HPRT1 Antibody

Binding Specificity: AA 17-185

Purpose: Zebrafish Hprt1 Antibody / Hypoxanthine phosphoribosyltransferase

Purification: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish HPRT1 recombinant protein (amino acids Y17-D185) was used as the immunogen for the Zebrafish Hprt1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal dilution of the Zebrafish HPRT1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Zebrafish Hprt1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for HPRT1

Target: HPRT1 (Hypoxanthine phosphoribosyltransferase 1 (HPRT1))

Alternative Name: Hprt1

Background: Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) is an enzyme encoded in humans by the HPRT1 gene. The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.

UniProt: Q7ZV49

Pathways: Ribonucleoside Biosynthetic Process