HPRT1 antibody (AA 17-186)

Catalog No. ABIN7871211

The Rabbit Polyclonal anti-HPRT1 antibody is suitable to detect HPRT1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, FACS and IF.

Quick Overview for HPRT1 antibody (AA 17-186) (ABIN7871211)

Target: HPRT1 (Hypoxanthine phosphoribosyltransferase 1 (HPRT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HPRT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Product Details anti-HPRT1 Antibody

Binding Specificity: AA 17-186

Purpose: HGPRTase Antibody / HPRT1

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids Y17-K186) was used as the immunogen for the HGPRTase antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the HGPRTase antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the HGPRTase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for HPRT1

Target: HPRT1 (Hypoxanthine phosphoribosyltransferase 1 (HPRT1))

Alternative Name: HGPRTase

Background: Hypoxanthine-guanine phosphoribosyltransferase (HGPRT, HGPRTase) is an enzyme encoded in humans by the HPRT1 gene. The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.

UniProt: P00492

Pathways: Ribonucleoside Biosynthetic Process