DCK antibody (AA 17-260)

Catalog No. ABIN7871215

The Mouse Monoclonal anti-DCK antibody (Clone 3G10) (ABIN7871215) specifically detects DCK in WB, IF, IHC (p) and FACS. The antibody is reactive with Human samples.

Quick Overview for DCK antibody (AA 17-260) (ABIN7871215)

Target: DCK (Deoxycytidine Kinase (DCK))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DCK antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: 3G10

Product Details anti-DCK Antibody

Binding Specificity: AA 17-260

Purpose: DCK Antibody

Purification: Affinity purified

Immunogen: A human recombinant protein (amino acids E17-L260) was used as the immunogen for the DCK antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the DCK antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the DCK antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for DCK

Target: DCK (Deoxycytidine Kinase (DCK))

Alternative Name: DCK

Background: Deoxycytidine kinase (dCK) is an enzyme which is encoded by the DCK gene in humans. Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.

UniProt: P27707