ZNF488 antibody (AA 170-307)

Catalog No. ABIN7871250

The Mouse Monoclonal anti-ZNF488 antibody is suitable to detect ZNF488 in samples from Human. It has been validated for FACS and IHC (p).

Quick Overview for ZNF488 antibody (AA 170-307) (ABIN7871250)

Target: ZNF488 (Zinc Finger Protein 488 (ZNF488))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ZNF488 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: PCRP-ZNF488-2D8

Product Details anti-ZNF488 Antibody

Binding Specificity: AA 170-307

Purpose: ZNF488 Antibody

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein (within amino acids 170-307) from the human protein was used as the immunogen for the ZNF488 antibody.

Isotype: IgG2a

Application Details

Application Notes: Optimal dilution of the ZNF488 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the ZNF488 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for ZNF488

Target: ZNF488 (Zinc Finger Protein 488 (ZNF488))

Alternative Name: ZNF488

Background: Zinc finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc finger proteins contain a Kruppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF488 is a 340 amino acid transcriptional regulator belonging to the Kruppel C2H2-type zinc finger protein family. ZNF488 localizes to the nucleus and contains two C2H2-type zinc fingers. ZNF488 is encoded by a gene located on chromosome 10, which contains a plethora of interesting genes and represents between 4 and 4.5 percent of the total DNA in cells. Jackson-Weiss, Cowden and Usher syndromes are a few diseases related to genes on chromosome 10.

UniProt: Q96MN9