Cadherin 4 antibody (AA 175-203)

Catalog No. ABIN7871300

This Rabbit Polyclonal antibody specifically detects Cadherin 4 in WB, IF, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Cadherin 4 antibody (AA 175-203) (ABIN7871300)

Target: Cadherin 4 (CDH4)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin 4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Cadherin 4 Antibody

Binding Specificity: AA 175-203

Purpose: Cadherin 4 Antibody / CDH4 / R-Cadherin

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 175-203 from the human protein was used as the immunogen for the Cadherin 4 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Cadherin 4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot the Cadherin 4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Cadherin 4

Target: Cadherin 4 (CDH4)

Alternative Name: Cadherin 4

Background: CDH4 is a classical cadherin from the cadherin superfamily. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization.

UniProt: P55283

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size