ADRB3 antibody (AA 179-250)

Catalog No. ABIN7871350

The Rabbit Polyclonal anti-ADRB3 antibody (ABIN7871350) specifically detects ADRB3 in WB, ELISA and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for ADRB3 antibody (AA 179-250) (ABIN7871350)

Target: ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADRB3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-ADRB3 Antibody

Binding Specificity: AA 179-250

Purpose: Beta 3 Adrenergic Receptor Antibody / ADRB3

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids R179-S250) was used as the immunogen for the Beta 3 Adrenergic Receptor antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Beta 3 Adrenergic Receptor antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Beta 3 Adrenergic Receptor antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ADRB3

Target: ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))

Alternative Name: Beta 3 Adrenergic Receptor

Background: The beta-3 adrenergic receptor, also known as ADRB3, is a beta-adrenergic receptor, and also denotes the human gene encoding it. It is mapped to 8p11.23. The protein encoded by this gene belongs to the family of beta adrenergic receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Obesity and bodyweight-related disorders are correlated with certain polymorphisms in three subtypes of beta-adrenoceptor, among them, the ADRB3 gene.

UniProt: P13945

Pathways: cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Brown Fat Cell Differentiation