Interleukin 17a antibody (AA 18-150)

Catalog No. ABIN7871394

The Rabbit Polyclonal anti-Interleukin 17a antibody is suitable to detect Interleukin 17a in samples from Mouse and Rat. It has been validated for ELISA and IHC (p).

Quick Overview for Interleukin 17a antibody (AA 18-150) (ABIN7871394)

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Interleukin 17a antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Interleukin 17a Antibody

Binding Specificity: AA 18-150

Purpose: Il-17a Antibody / Ctla-8

Purification: Antigen affinity purified

Immunogen: Recombinant rat protein (amino acids A18-S150) was used as the immunogen for the Il-17a antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Il-17a antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Il-17a antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Interleukin 17a

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Alternative Name: Il-17a

Background: Interleukin-17A is a protein that in humans is encoded by the IL17A gene. The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

UniProt: Q61453