Fission 1 antibody (AA 18-152)

Catalog No. ABIN7871395

The Rabbit Polyclonal anti-Fission 1 antibody (ABIN7871395) specifically detects Fission 1 in WB, ELISA, IF and IHC (p). The antibody is reactive with Human and Rat samples.

Quick Overview for Fission 1 antibody (AA 18-152) (ABIN7871395)

Target: Fission 1 (FIS1)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fission 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Fission 1 Antibody

Binding Specificity: AA 18-152

Purpose: FIS1 Antibody / TTC11

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids E18-S152) was used as the immunogen for the FIS1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the FIS1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the FIS1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Fission 1

Target: Fission 1 (FIS1)

Alternative Name: FIS1

Background: Mitochondrial fission 1 protein (FIS1) is a protein that in humans is encoded by the FIS1 gene on chromosome 7. It is mapped to 7q22.1. The balance between fission and fusion regulates the morphology of mitochondria. TTC11 is a component of a mitochondrial complex that promotes mitochondrial fission. Its role in mitochondrial fission thus implicates it in the regulation of mitochondrial morphology, the cell cycle, and apoptosis. By extension, the protein is involved in associated diseases, including neurodegenerative diseases and cancers.

UniProt: Q9Y3D6

Pathways: Positive Regulation of Endopeptidase Activity