D Amino Acid Oxidase antibody (AA 18-338)

Catalog No. ABIN7871408

This Rabbit Polyclonal antibody specifically detects D Amino Acid Oxidase in WB, ELISA and FACS. It exhibits reactivity toward Human and Mouse.

Quick Overview for D Amino Acid Oxidase antibody (AA 18-338) (ABIN7871408)

Target: D Amino Acid Oxidase (DAO) (D-Amino-Acid Oxidase (DAO))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This D Amino Acid Oxidase antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-D Amino Acid Oxidase Antibody

Binding Specificity: AA 18-338

Purpose: D-amino-acid oxidase Antibody / DAO

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids C18-K338) was used as the immunogen for the D-amino-acid oxidase antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the D-amino-acid oxidase antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the D-amino-acid oxidase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for D Amino Acid Oxidase

Target: D Amino Acid Oxidase (DAO) (D-Amino-Acid Oxidase (DAO))

Alternative Name: D-amino-acid oxidase

Background: D-amino acid oxidase (DAAO, also OXDA, DAMOX) is an enzyme with the function on a molecular level to oxidize D-amino acids to the corresponding alpha-keto acids, producing ammonia and hydrogen peroxide. This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known, it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia.

UniProt: P14920