Calmegin antibody (AA 18-611)
Quick Overview for Calmegin antibody (AA 18-611) (ABIN7871433)
Target
See all Calmegin (CLGN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 18-611
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Purpose
- Clgn Antibody / Calmegin
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Purification
- Antigen affinity purified
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Immunogen
- Recombinant mouse protein (amino acids N18-D611) was used as the immunogen for the Clgn antibody.
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Isotype
- IgG
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Application Notes
- Optimal dilution of the Clgn antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Storage
- 4 °C,-20 °C
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Storage Comment
- After reconstitution, the Clgn antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Calmegin (CLGN)
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Alternative Name
- Clgn
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Background
- Calmegin, also known as CLGN, is a protein which in humans is encoded by the CLGN gene. This gene belongs to the calreticulin family, which includes calreticulin, calnexin, and calmegin, and encodes a calcium-binding molecular chaperone specifically expressed in pachytene stage male germ cells. It is required for the proper folding of newly synthesized membrane proteins in the endoplasmic reticulum including those critical for sperm migration from the uterus into the oviduct and sperm adhesion to and penetration of the zona pellucida. This gene plays a key role in spermatogenesis and male infertility. Alternative splice variants exist for this gene.
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UniProt
- P52194
Target
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