CXCR5 antibody (AA 181-358)

Catalog No. ABIN7871457

The Rabbit Polyclonal anti-CXCR5 antibody is suitable to detect CXCR5 in samples from Human, Mouse and Rat. It has been validated for FACS, WB and ELISA.

Quick Overview for CXCR5 antibody (AA 181-358) (ABIN7871457)

Target: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR5 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), ELISA

Product Details anti-CXCR5 Antibody

Binding Specificity: AA 181-358

Purpose: MDR15 Antibody / CXCR5 / BLR1

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids A181-S358) was used as the immunogen for the MDR15 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the MDR15 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the MDR15 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for CXCR5

Target: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Alternative Name: MDR15

Background: CXCR5 (Chemokine CXC Motif Receptor 5), also known as BLR1 (Burkitt lymphoma receptor 1) and MDR15 (Monocyte derived receptor 15), is a G protein-coupled seven transmembrane receptor for chemokine CXCL13(also known as BLC) and belongs to the CXC chemokine receptor family. In humans, the CXC-R5 protein is encoded by the CXCR5 gene. The gene plays an essential role in B cell migration. Reif et al.(2002) concluded that their findings defined the mechanism of B-cell relocalization in response to antigen, and established that cell position in vivo can be determined by the balance of responsiveness to chemoattractants made in separate but adjacent zones. Chan et al.(2003) investigated the expression of chemokines and chemokine receptors in eyes with primary intraocular B-cell lymphoma(PIOL).

UniProt: P32302