NAPSA antibody (AA 189-299)

Catalog No. ABIN7871528

This Mouse Monoclonal antibody specifically detects NAPSA in IHC (p). It exhibits reactivity toward Human.

Quick Overview for NAPSA antibody (AA 189-299) (ABIN7871528)

Target: NAPSA (Napsin A Aspartic Peptidase (NAPSA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NAPSA antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: NAPSA-3307

Product Details anti-NAPSA Antibody

Binding Specificity: AA 189-299

Purpose: Napsin A Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: Amino acids 189-299 from the human protein were used as the immunogen for the Napsin A antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the Napsin A antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the Napsin A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for NAPSA

Target: NAPSA (Napsin A Aspartic Peptidase (NAPSA))

Alternative Name: Napsin A

Background: Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B. There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.

UniProt: O96009

Pathways: Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis