ITGA6 antibody (AA 189-917)

Catalog No. ABIN7871539

The Rabbit Polyclonal anti-ITGA6 antibody (ABIN7871539) specifically detects ITGA6 in WB, FACS and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ITGA6 antibody (AA 189-917) (ABIN7871539)

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA6 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Product Details anti-ITGA6 Antibody

Binding Specificity: AA 189-917

Purpose: Integrin alpha 6 Antibody / ITGA6

Purification: Affinity purified

Immunogen: Amino acids Q189-K917 from the human protein were used as the immunogen for the Integrin alpha 6 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Integrin alpha 6 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: Store the Integrin alpha 6 antibody at -20oC.

Target Details for ITGA6

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Alternative Name: Integrin alpha 6

Background: Integrin alpha-6, also called VLA-6 or ITGA6B is a protein that in humans is encoded by the ITGA6 gene. This gene is mapped to 2q31.1. The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome.

UniProt: P23229

Pathways: CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex