Nitric Oxide Synthase antibody (AA 19-1320)

Catalog No. ABIN7871558

This Rabbit Polyclonal antibody specifically detects Nitric Oxide Synthase in ELISA, WB and FACS. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Nitric Oxide Synthase antibody (AA 19-1320) (ABIN7871558)

Target: Nitric Oxide Synthase (NOS)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nitric Oxide Synthase antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-Nitric Oxide Synthase Antibody

Binding Specificity: AA 19-1320

Purpose: Nitric oxide synthase Antibody Antibody / NOS1 / nNOS

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids R19-E1320) was used as the immunogen for the Nitric oxide synthase antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Nitric oxide synthase antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Nitric oxide synthase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Nitric Oxide Synthase

Target: Nitric Oxide Synthase (NOS)

Alternative Name: Nitric oxide synthase

Background: Nitric oxide synthase 1 (neuronal), also known as NOS1, is an enzyme that in humans is encoded by the NOS1 gene. The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.

UniProt: P29475

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process