SBDS antibody (AA 19-241)

Catalog No. ABIN7871577

The Rabbit Polyclonal anti-SBDS antibody is suitable to detect SBDS in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IF and FACS.

Quick Overview for SBDS antibody (AA 19-241) (ABIN7871577)

Target: SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SBDS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-SBDS Antibody

Binding Specificity: AA 19-241

Purpose: SBDS Antibody / Shwachman-Bodian-Diamond syndrome protein

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids R19-D241) was used as the immunogen for the SBDS antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SBDS antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the SBDS antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SBDS

Target: SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

Alternative Name: SBDS

Background: Ribosome maturation protein SBDS is a protein that in humans is encoded by the SBDS gene. This gene encodes a highly conserved protein that plays an essential role in ribosome biogenesis. The encoded protein interacts with elongation factor-like GTPase 1 to disassociate eukaryotic initiation factor 6 from the late cytoplasmic pre-60S ribosomal subunit allowing assembly of the 80S subunit. Mutations within this gene are associated with the autosomal recessive disorder Shwachman-Bodian-Diamond syndrome. This gene has a closely linked pseudogene that is distally located.

UniProt: Q9Y3A5

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly