LUM antibody (AA 19-338)

Catalog No. ABIN7871587

The Rabbit Polyclonal anti-LUM antibody (ABIN7871587) specifically detects LUM in WB, ELISA, FACS and IHC (p). The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for LUM antibody (AA 19-338) (ABIN7871587)

Target: LUM (Lumican (LUM))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LUM antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-LUM Antibody

Binding Specificity: AA 19-338

Purpose: Lumican Antibody / LUM

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (amino acids Q19-N338) was used as the immunogen for the Lumican antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Lumican antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Lumican antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for LUM

Target: LUM (Lumican (LUM))

Alternative Name: Lumican

Background: Lumican, also known as LUM, is an extracellular matrix protein that, in humans, is encoded by the LUM gene on chromosome 12. This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.

UniProt: P51884

Pathways: Glycosaminoglycan Metabolic Process