MFAP3 antibody (AA 19-349)

Catalog No. ABIN7871588

This Rabbit Polyclonal antibody specifically detects MFAP3 in ELISA, WB, FACS and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MFAP3 antibody (AA 19-349) (ABIN7871588)

Target: MFAP3 (Microfibrillar Associated Protein 3 (MFAP3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MFAP3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MFAP3 Antibody

Binding Specificity: AA 19-349

Purpose: MFAP3 Antibody / Microfibril-associated glycoprotein 3

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (A19-N349) was used as the immunogen for the MFAP3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the MFAP3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the MFAP3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for MFAP3

Target: MFAP3 (Microfibrillar Associated Protein 3 (MFAP3))

Alternative Name: MFAP3

Background: Microfibril-associated glycoprotein 3 (MFAP3), is a member of the MFAP family which play a role in microfibril assembly, elastinogenesis, and tissue homeostasis. The family members were identified as potential components of fibrillin-containing microfibrils, but they do not share structural similarities. MFAP3 is found in ocular zonules. Human MFAP3 is a serine-rich acidic protein located in zonular fibers and consists of an extracellular domain (ECD) containing one Ig-like C2-type domain, a single transmembrane domain, and a cytoplasmic domain. Within the ECD, mature human MFAP3 shares 74 % amino acid sequence identity with mouse and rat MFAP3. Among MFAP3-related pathways are degradation of the extracellular matrix and elastic fiber formation. MFAP is a candidate gene for heritable diseases affecting microfibrils.

UniProt: P55082