DOCK4 antibody (AA 191-1837)

Catalog No. ABIN7871652

The Rabbit Polyclonal anti-DOCK4 antibody is suitable to detect DOCK4 in samples from Human and Rat. It has been validated for WB, ELISA, IHC (p) and FACS.

Quick Overview for DOCK4 antibody (AA 191-1837) (ABIN7871652)

Target: DOCK4 (Dedicator of Cytokinesis 4 (DOCK4))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOCK4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-DOCK4 Antibody

Binding Specificity: AA 191-1837

Purpose: DOCK4 Antibody / Dedicator of cytokinesis protein 4

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids K191-I1837) was used as the immunogen for the DOCK4 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the DOCK4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the DOCK4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for DOCK4

Target: DOCK4 (Dedicator of Cytokinesis 4 (DOCK4))

Alternative Name: DOCK4

Background: This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized.

UniProt: Q8N1I0