RORA antibody (AA 193-222)
Quick Overview for RORA antibody (AA 193-222) (ABIN7871680)
Target
See all RORA AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 193-222
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Purpose
- ROR alpha Antibody / RORA
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Purification
- Antigen affinity purified
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Immunogen
- A portion of amino acids 193-222 from the human protein was used as the immunogen for the ROR alpha antibody.
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Isotype
- Ig Fraction
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Application Notes
- The stated application concentrations are suggested starting points. Titration of the ROR alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the ROR alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- RORA (RAR-Related Orphan Receptor A (RORA))
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Alternative Name
- ROR alpha
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Background
- RORA is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene.
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UniProt
- P35398
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Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
Target
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