MYT1L antibody (AA 195-825)

Catalog No. ABIN7871706

The Rabbit Polyclonal anti-MYT1L antibody is suitable to detect MYT1L in samples from Human. It has been validated for WB, ELISA, IF and FACS.

Quick Overview for MYT1L antibody (AA 195-825) (ABIN7871706)

Target: MYT1L (Myelin Transcription Factor 1-Like (MYT1L))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYT1L antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-MYT1L Antibody

Binding Specificity: AA 195-825

Purpose: MYT1L Antibody / Myelin transcription factor 1-like protein

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (D195-K825) was used as the immunogen for the MYT1L antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the MYT1L antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the MYT1L antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for MYT1L

Target: MYT1L (Myelin Transcription Factor 1-Like (MYT1L))

Alternative Name: MYT1L

Background: Myelin transcription factor 1 like is a protein that in humans is encoded by the MYT1L gene. This gene encodes a member of the zinc finger superfamily of transcription factors whose expression, thus far, has been found only in neuronal tissues. The encoded protein belongs to a novel class of cystein-cystein-histidine-cystein zinc finger proteins that function in the developing mammalian central nervous system. Forced expression of this gene in combination with the basic helix-loop-helix transcription factor NeuroD1 and the transcription factors POU class 3 homeobox 2 and achaete-scute family basic helix-loop-helix transcription factor 1 can convert fetal and postnatal human fibroblasts into induced neuronal cells, which are able to generate action potentials. Mutations in this gene have been associated with an autosomal dominant form of cognitive disability and with autism spectrum disorder. Alternative splicing results in multiple variants.

UniProt: Q9UL68